Atoms with all states of the major shells occupied exhibit a high stability against removal or addition of an electron. difficile resistance to clindamycin and have resolved with restriction of the antibiotic.
Serine is the most important source of substituted folates for biosynthetic reactions, and the activity of serine hy- VITAMINS MINERALS 493 COO OHH CH HN C N CH NN210 H 5 N H HC O O H2N N H2N N NH CO (Glu)n N CH2 Tetrahydrofolate (THF) CH2 HC O OH H N CH2 N OH H N CH2 N H 5-Formyl THF N H2N N NH 10-Formyl THF HC NH OHHH OHCH2 N N CH2 N N N CH2 N H2N N NH 5-Formimino THF H2N N NH 5,10-Methylene THF CH3 H2N OHHH OHCH N CH2 N N CH2 N NN N N 5-Methyl THF H2N N N 5,10-Methenyl THF HH Sources of one-carbon units Serine Glycine Choline Formimino-THF Formate Synthesis using one-carbon units Serine Methylene-THF Methenyl-THF Formyl-THF Methyl-THF TMP dihydrofolate DNA Formyl-methionine Purines Methionine Histidine CO2 Figure 4516.
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