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597 5. 2) can be understood both as the variance in the direction of the smallest χ2 between each data point and the line with slope b, and also as the variance of the linear combination yi a bxi of two random variables xi and yiVar(yi a bxi) Var(yi) b2Var(xi) σ2 b2σ2 1wi (15. Alternatively, diester derivatives of para- meta- or ant acid can be readily synthesised by acid- catalysed esteriWcation of the carboxyl group, followed by pyridine-catalysed acylation of the phenolic hydroxyl group (see Figure A3.
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